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Utility of the Malayalam translation of the 7- minute screen for Alzheimer’s disease risk in an Indian community
Alzheimer’s disease (AD) is suspected to be currently under-diagnosed in India, thus the need for a brief, effective screening test for the condition. Aims: We aimed to test the Malayalam translation of the 7-Minute Screen (7MS) for detecting those at high risk for AD and to report on the subscores...
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| Format: | Printed Book |
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Neurology India
2008
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| Online Access: | http://10.26.1.76/ks/005823.pdf |
| LEADER | 02344nam a22001457a 4500 | ||
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| 100 | |a Celeste A. de Jager, Madhav Thambisetty, K. V. Praveen, P. D. Sheeba, K. N. Ajini, A. Sajeev, K. K. Smitha, L. P. Rahmathulla, T. Ramakrishna and Smith A. David |9 30804 | ||
| 245 | |a Utility of the Malayalam translation of the 7- minute screen for Alzheimer’s disease risk in an Indian community | ||
| 260 | |b Neurology India |c 2008 | ||
| 300 | |b April-June 2008 Vol 56 Issue 2 | ||
| 520 | |a Alzheimer’s disease (AD) is suspected to be currently under-diagnosed in India, thus the need for a brief, effective screening test for the condition. Aims: We aimed to test the Malayalam translation of the 7-Minute Screen (7MS) for detecting those at high risk for AD and to report on the subscores used to derive the Alzheimer’s risk score. Setting and Design: This study was performed in Kerala State amongst young university students and elders in residential care homes. Materials and Methods: Two hundred and eighty-two volunteers were tested, 178 young controls (aged 20-29) and 104 literate elders, (55-92 years). None were clinically diagnosed with AD. Statistical Analyses: Elders and controls were assessed as High or Low AD Risk with the published 7MS algorithm. Performance was compared between groups with ANOVA. Results: The algorithm estimated high (n = 61/104) or low (n = 40/104) AD risk in the elderly. SigniÞ cant differences were found between controls, low- and high-risk groups on all four components of the screen (Orientation: F = 131.1, Enhanced Cued Recall: F = 23.4, Clock Drawing: F = 65.1, Verbal Fluency: F = 15.7, P < 0.0001 for all) and in the risk scores (F = 144.7, P < 0.0001). Age and gender affected verbal ß uency, orientation and clock drawing performance. The high-risk group had worse scores for orientation and better scores for memory than previously reported for AD cases in other populations. Conclusions: The 7MS may be a useful screening test for cognitive impairment in India. Suggestions are given for revising the ‘risk algorithm’ for more appropriate AD risk assessment in this population. | ||
| 650 | |a COGNITIVE IMPAIRMENT; |a ELDERLY; |a MEMORY |9 30805 | ||
| 856 | |u http://10.26.1.76/ks/005823.pdf | ||
| 942 | |c KS | ||
| 999 | |c 81525 |d 81525 | ||
| 952 | |0 0 |1 0 |4 0 |7 0 |9 73616 |a MGUL |b MGUL |d 2016-04-18 |l 0 |r 2016-04-18 |w 2016-04-18 |y KS | ||